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found that PF therapy plays a positive role in neural and emotional regulation by reversing the decreased expression of BDNF and p-CREB in the hippocampus caused by the MCAO and CUMS model (Hu et al., 2019)

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Epidemiological evidence linking disrupted Copper homeostasis with MASLD Putative pathomechanisms involved Copper deficiency Copper deficiency may potentially increase the risk of MASLD and fibrosing MASH through a variety of pathomechanisms that result from altered energy homeostasis, dysfunctional lipid metabolism, a pro-inflammatory prostaglandin profile, increased lipid peroxidation, and decreased antioxidant defense